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Elevate & Educate: Transforming Eye Care

Create your own ripple effect... Shared knowledge is the cornerstone of progress. By teaching each other and also encouraging a shared philosophy of practice, we can bridge the rapidly growing void between medicine and common eye care. Surgical Ophthalmology <=> MEDICAL VOID <=> Common Eyecare. S...

by John R Martinelli MD OD FAAO — Jan 06, 2025

Angle Closure & Osteoporosis Treatment

Why do bisphosphonates increase risk?... There appears to be a significant association between bisphosphonate use and the risk of angle closure glaucoma in patients with osteoporosis. A retrospective cohort study reviewing over 200,000 patients found individuals being treated with bisphosphonate...

by John R Martinelli MD OD FAAO — Jan 03, 2025

The Story Of Ocular Immunology

The eye on the daily front lines... The evolution of the ocular immune system is a fascinating journey spanning billions of years. This complex system emerged from primitive cellular responses, with innate immunity taking shape around 2.5 billion years ago. Over time, the development of adaptive...

by John R Martinelli MD OD FAAO — Dec 31, 2024

Diabetic Retinopathy Risks In Younger Age

The first three also matter... Recent study findings have identified eight independent risk factors for diabetic retinopathy (DR) in younger and middle-aged individuals. Place of residence, education level, medical payment method, BMI, disease duration, hyperlipidemia, physical activity level, an...

by John R Martinelli MD OD FAAO — Dec 26, 2024

Topical Treatment For ARMD?

Eyedrops may be just on the horizon... Toll-Like Receptors (TLRs) play a key role in retinal inflammation, and recently a brilliant study has pointed to the potential of TDIP (Toll/interleukin-1 receptor derived immunomodulatory peptides) eye drops in targeting and combating sodium iodate (NaIO3)...

by John R Martinelli MD OD FAAO — Dec 24, 2024

Anti-VEGF's & Glaucoma

What do you tell your patients?... The possible association between intravitreal anti-VEGF injections and the development of ocular hypertension or primary open-angle glaucoma has likely been a concern for all of us who follow these individuals in daily practice. Anti-VEGF agents, while revoluti...

by John R Martinelli MD OD FAAO — Dec 20, 2024

Thick Corneas & Increased Glaucoma Risk?

Maybe just throw away your pachymeter... Contrary to our usual thinking, today the British Journal of Ophthalmology (BJO) released a powerful Mendelian randomization study revealing a positive correlation between central corneal thickness (CCT) and primary open-angle glaucoma (POAG). The research...

by John R Martinelli MD OD FAAO — Dec 17, 2024

Photobiomodulation for Retinitis Pigmentosa

Do you know the how & why? There has been promising results utilizing photobiomodulation as a potential treatment for retinitis pigmentosa (RP), as well as other retinal conditions such as macular degeneration (AMD), Stargardt's, and diabetic retinopathy. Recent findings utilizing multiwavelength...

by John R Martinelli MD OD FAAO — Dec 14, 2024

Omega 3's & AMD

Should they be part of your treatment plan? There is new information on the potential protective role of omega-3 fatty acids against age-related macular degeneration (AMD). A recent large-scale prospective cohort study and Mendelian randomization analyses suggest a causal link between higher pla...

by John R Martinelli MD OD FAAO — Dec 10, 2024

Nitric Oxide, OCTA & Glaucoma

NO3 via Vyzulta (latanoprostene bunod) may just matter. A recent investigation was published regarding the impact of latanoprostene bunod on optical coherence tomography angiography (OCT-A) parameters in newly diagnosed open-angle glaucoma patients. Changes in both vessel density and intraocular...

by John R Martinelli MD OD FAAO — Dec 05, 2024

Vision & Neurology Casebook Complementary Podcast

FREE ACCESS: Vision & Neurology...In Conversation GO TO PODCAST What you'll get: 25 Real-World Cases 55:54 Audio Only Differential Diagnosis in Neuro-Ophthalmic Disorders Importance of Patient History and Examination The Art of Patient Management Listen & Learn EyeX Podcast Subscr...

by John R Martinelli MD OD FAAO — Dec 01, 2024

Keratoconus Podcast 2024 Update

Happy Thanksgiving Everyone! Here is a complementary link to access the EyeX Keratoconus Podcast 2024 Update. FREE Bonus Episode: Listen to the latest advances and treatment options for Keratoconus in 2024 (16:10 Audio Only). SIGN ON & LISTEN SIGN ON & LISTEN Author: John R. Martinelli, MD, ...

by John R. Martinelli MD OD FAAO — Nov 28, 2024

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MedEye Minute Newsletter

Brief clinical reviews of things that matter.