Should they be part of your treatment plan?
There is new information on the potential protective role of omega-3 fatty acids against age-related macular degeneration (AMD).
A recent large-scale prospective cohort study and Mendelian randomization analyses suggest a causal link between higher plasma levels of omega-3 polyunsaturated fatty acids (PUFAs) and reduced AMD risk. Specifically, each 1 mmol/L increase in plasma omega-3 PUFAs or docosahexaenoic acid (DHA) was associated with a 20% and 35% reduction in AMD incidence over 13 years, respectively. These findings are particularly noteworthy given the anti-inflammatory and anti-angiogenic properties of omega-3s. However, it's important to note previous clinical trials have found inconsistent results, possibly due to methodological limitations.
This new evidence highlights the need for us to consider omega-3 fatty acids as a potential preventive strategy for AMD, while pointing to the importance of additional research to establish optimal dosage recommendations and long-term efficacy.
-JRM
Go to the article in Ophthalmology:
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