The Ophthalmic Physician Newsletter

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Diabetic Retinopathy Risks In Younger Age

The first three also matter... Recent study findings have identified eight independent risk factors for diabetic retinopathy (DR) in younger and middle-aged individuals. Place of residence, education level, medical payment method, BMI, disease duration, hyperlipidemia, physical activity level, an...

by John R Martinelli MD OD FAAO — Dec 26, 2024

Topical Treatment For ARMD?

Eyedrops may be just on the horizon... Toll-Like Receptors (TLRs) play a key role in retinal inflammation, and recently a brilliant study has pointed to the potential of TDIP (Toll/interleukin-1 receptor derived immunomodulatory peptides) eye drops in targeting and combating sodium iodate (NaIO3)...

by John R Martinelli MD OD FAAO — Dec 24, 2024

Anti-VEGF's & Glaucoma

What do you tell your patients?... The possible association between intravitreal anti-VEGF injections and the development of ocular hypertension or primary open-angle glaucoma has likely been a concern for all of us who follow these individuals in daily practice. Anti-VEGF agents, while revoluti...

by John R Martinelli MD OD FAAO — Dec 20, 2024

Thick Corneas & Increased Glaucoma Risk?

Maybe just throw away your pachymeter... Contrary to our usual thinking, today the British Journal of Ophthalmology (BJO) released a powerful Mendelian randomization study revealing a positive correlation between central corneal thickness (CCT) and primary open-angle glaucoma (POAG). The research...

by John R Martinelli MD OD FAAO — Dec 17, 2024

Photobiomodulation for Retinitis Pigmentosa

Do you know the how & why? There has been promising results utilizing photobiomodulation as a potential treatment for retinitis pigmentosa (RP), as well as other retinal conditions such as macular degeneration (AMD), Stargardt's, and diabetic retinopathy. Recent findings utilizing multiwavelength...

by John R Martinelli MD OD FAAO — Dec 14, 2024

Omega 3's & AMD

Should they be part of your treatment plan? There is new information on the potential protective role of omega-3 fatty acids against age-related macular degeneration (AMD). A recent large-scale prospective cohort study and Mendelian randomization analyses suggest a causal link between higher pla...

by John R Martinelli MD OD FAAO — Dec 10, 2024

Nitric Oxide, OCTA & Glaucoma

NO3 via Vyzulta (latanoprostene bunod) may just matter. A recent investigation was published regarding the impact of latanoprostene bunod on optical coherence tomography angiography (OCT-A) parameters in newly diagnosed open-angle glaucoma patients. Changes in both vessel density and intraocular...

by John R Martinelli MD OD FAAO — Dec 05, 2024

Vision & Neurology Casebook Complementary Podcast

FREE ACCESS: Vision & Neurology...In Conversation GO TO PODCAST What you'll get: 25 Real-World Cases 55:54 Audio Only Differential Diagnosis in Neuro-Ophthalmic Disorders Importance of Patient History and Examination The Art of Patient Management Listen & Learn EyeX Podcast Subscr...

by John R Martinelli MD OD FAAO — Dec 01, 2024

Keratoconus Podcast 2024 Update

Happy Thanksgiving Everyone! Here is a complementary link to access the EyeX Keratoconus Podcast 2024 Update. FREE Bonus Episode: Listen to the latest advances and treatment options for Keratoconus in 2024 (16:10 Audio Only). SIGN ON & LISTEN SIGN ON & LISTEN Author: John R. Martinelli, MD, ...

by John R. Martinelli MD OD FAAO — Nov 28, 2024

Diagnostic Errors of The Ocular Surface

Anchoring & Ambiguous Diagnostic Terminology This was the topic of an article in JAMA Ophthalmology last week. Diagnostic errors of the ocular surface pose a significant issue, with far-reaching implications for patient care and safety. Misdiagnosis of dry eye, overlooking underlying conditions, ...

by John R Martinelli MD OD FAAO — Nov 22, 2024

EyeX AI Powered Podcast Launch

AI Powered Medical Reviewers Discuss & Keep It Simple IN CONVERSATION: Dr. Martinelli's Vision & Neurology Casebook55:54 (Audio) GO TO PODCAST Listen to The Conversation: Is it Muscle, Nerve, or Brain? Differential Diagnosis in Neuro-Ophthalmic Disorders: Listen to the discussion concentrating...

by John R Martinelli MD OD FAAO — Nov 21, 2024

Amblyopia & Hearing Loss

Mom asks if there is a link...what do you say? There is an interesting association between amblyopia and an increased risk of hearing loss, particularly sensorineural hearing loss (SNHL). A propensity-matched analysis showed children with amblyopia have a 9% higher overall risk of experiencing he...

by John R Martinelli MD OD FAAO — Nov 17, 2024

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